Which of the situations below will enhance microtubule shrinkage?

Which of the situations below will enhance microtubule shrinkage?



(a) addition of a drug that inhibits GTP exchange on free tubulin dimers
(b) addition of a drug that inhibits hydrolysis of the GTP carried by tubulin dimers
(c) addition of a drug that increases the affinity of tubulin molecules carrying GDP for other tubulin molecules
(d) addition of a drug that blocks the ability of a tubulin dimer to bind to ?-tubulin



Answer: 




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